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This titration schedule is conservative compared to what some providers offer

(9) Portha B, et al

A clinician may consider it when a person with type 2 diabetes needs both metformin and an SGLT2 inhibitor as part of a broader plan

Lack of Clinical Data : The safety and efficacy data supporting tirzepatide use come exclusively from studies using FDA-approved formulations

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Intestinal proliferation and delayed intestinal transit in a patient with a GLP-1-, GLP-2- and PYY-producing neuroendocrine carcinoma