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Many infants with CACT deficiency do not survive the newborn period

These often include: Amoxicillin: A widely used penicillin-type antibiotic effective against a broad range of bacterial infections

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Though the normal intestinal microbiome does not include large amounts of pathogenic organisms, as an example, increased proliferation of the pathogen Clostridium botulinum is associated with release of botulinum neurotoxins, damaging the intestinal barrier and fostering absorption of the neurotoxin into the systemic circulation and the nervous system, causing botulism [49]