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Conversely, the overexpression of Parkin resulted in a reduction in the number of neurons lost in the motor cortex of TDP-43 model animals while also inhibiting the degenerative phenotype observed in hTDP-43 model animals (Hebron et al., 2014)

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blood, urine) are derived by statistical methods from surveys and repeated measures of chemicals, and further used by the German HBM Commission to define concentrations (HBM-I and HBM-II) with no increased risk for adverse health effects or with the need for intervention to reduce an exposure (Umwelt Bundesamt, 2023)

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