Acknowledgements This work was supported by grants from the National multidisciplinary collaborative diagnosis and treatment capacity building project for major diseases (TJZ202104), the Natural Science Foundation of China (82270643, 82070644, 82170621 and 82370645), the Science and Technology Major Program of Sichuan Province (2022ZDZX0019), the Sichuan Science and Technology Program (2024NSFSC0645), 1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University (ZYJC18008, ZYGD22006)
Several common factors break this system down
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The ability of curcumin to down-regulate the expression of fibronectin, one of the ECM proteins, which is overexpressed in leiomyoma as compared to normal myometrium, has also been documented ( Camellia sinensis (L.) Kuntze [Theaceae] (Green Tea) in Uterine Fibroids A randomized controlled trial reported on the effect of green tea extract [45% epigallocatechin gallate (EGCG)] in women with symptomatic UF showed a significant reduction in the fibroid volume as compared to the placebo group after taking 800 mg of green tea extract for the duration of 4 months