When cost is not an issue, the ADA recommends choosing a second-line medication from one of the following: dipeptidyl peptidase-4 inhibitors (DPP4i), glucagon-like peptide-1 receptor agonists (GLP-1-RA), or sodium/glucose co-transporter inhibitors (SGLT2i) [3]
While direct injection or shaking may produce a clear solution faster, clarity does not equal bioactivity
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The first is examining adherence: missing doses or inconsistent injection timing reduces the medication's effectiveness