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ccRCC often involves the reprogramming of glucose and lipid metabolism and the tricarboxylic acid cycle, as well as the alteration of tryptophan, arginine, and glutamine metabolism, all of which may provide potential biomarkers or treatment strategies (137)

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Good sources include lean meat, fish, eggs, dairy, legumes, and plant-based alternatives

GSH levels are highest in liver tissue, which is also a hub for lipid production

Whether the triple agonist mechanism translates into meaningfully greater clinical benefit over dual agonists in humans has not yet been established in head-to-head trials