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However, recent clinical and research findings indicate that vitiligo is caused by the body's immune system attacking melanocytes, the cells responsible for skin colour, not only in the skin but also in mucous membranes, the eyes, hair follicles, and the ears

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This structural damage causes further mitochondrial failure and even more ROS leakage, creating a continuous "doom loop" of profound energy depletion, systemic inflammation, and the hallmark symptom of post-exertional malaise (PEM)