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Methods: Patients eligible for PEDFIC 1 (NCT03566238) and PEDFIC 2 (NCT03659916) had elevated serum bile acids and significant pruritus at screening

[9] If a pregnant patient develops a condition where MB might otherwise be indicated (for example, a pregnant patient with acute methemoglobinemia from dapsone toxicity), physicians must weigh maternal life over fetal risk, but even then they may seek alternative treatments first (like high-dose ascorbic acid or hyperbaric oxygen) and resort to MB only if absolutely necessary

10.3389/fphar.2022.844961 Front Pharmacol

No one should exceed the recommended limits, and it must be taken under professional supervision

Unlike liquid supplements, which must be consumed quickly after opening, the powder form has a longer shelf life and is more stable

doi: 10.1002/bies.20769