These mechanisms contribute to the cardioprotective effects of GLP-1 RAs in diabetic myocardial diseases [105]
This is why a one size fits all approach often fails
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Your digestive system is already adjusting to continuous bile flow, and semaglutide slows stomach emptying further, so side effects may be more pronounced
doi:10.2337/diacare.22.3.503
This is particularly true for patients who were started on insulin early in their disease course when their beta cells still had significant function, gained weight on insulin therapy, have A1C levels that might respond to GLP-1-mediated insulin secretion, or want the cardiovascular and weight loss benefits that GLP-1 medications offer