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The most common ones are gastrointestinal, including nausea, vomiting, diarrhea, constipation, indigestion, and abdominal pain

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Injecting too shallow delivers the medication intradermally (into the skin itself), causing a painful welt and poor absorption

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He explains why tirzepatide was evaluated against dulaglutide, how blinding and dose escalation were managed, and what the data show about cardiovascular risk, metabolic effects, and tolerability