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As people get older, their ability to absorb vitamin B12 decreases

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Improper technique or contamination can lead to more serious localized issues such as injection site infection, abscess formation, tissue necrosis, or thrombophlebitis (vein inflammation)

A variety of serious health conditions are associated with elevated homocysteine, including: Is vitamin B12 hard on the kidneys

Known sensitivity to any component , including cobalt/B12 hypersensitivity

Lipotropes are substances that promote the removal of fat from the liver and reduce the production of fat