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Upon DMF treatment, the glutathionylation of a cysteine of sarco/endoplasmic reticulum Ca 2+ -ATPase SERCA2b is critical to the modulation of intracellular calcium concentration

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The concept of incretin effect was first proposed by Creutzfeldt in the 1970s ( 2 Physiology of incretins 2.1 Discoveries of GIP and GLP-1 The first incretin, GIP, was purified from canine intestinal extracts in the late 1960s ( + secretion ( Figure 1 Section A]

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Alternative delivery: While oral semaglutide was a big advance, other methods are being explored

A platinum-customized tetrode was hooked to the nerve fibers, and the electrode was connected to a multichannel recording and signal processing system (Powerlab 26/04, AD Instruments)