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A linear gradient of mobile phases was employed, where solvent A comprised 0.1% (v/v) formic acid (##1209246, Sigma Aldrich, Germany) and solvent B consisted of 80% (v/v) acetonitrile (##741857, Sigma Aldrich, USA) with 0.1% (v/v) formic acid

It is the most abundant and potent antioxidant in humans, plants, and animals

The dose of NTBC should be increased if the SA level increases once patient adherence has been confirmed

Research 427, S16S21