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Just when you thought you knew what to expect with GLP-1s, new research emerges that gives you pause

If side effects become limiting, the dose can be reduced or adjustments can be made to meal timing, hydration, or accompanying medications

Eur Urol Focus 5:756787

Elevated cerebrospinal fluid (CSF) leptin in idiopathic intracranial hypertension (IIH): evidence for hypothalamic leptin resistance

Structureactivity relations of the derivatives clearly demonstrated that the length of fatty di-acid was important, and that the C18 di-acid used in semaglutide was the optimal choice

GLP-1 has been shown to attenuate meal-induced gastric antral propagated contractions while increasing pyloric tone (159, 160)