While its especially helpful for those on GLP-1s, its also great for anyone focused on losing weight in a healthy, balanced way
The international clinical development of efpeglenatide was stopped, despite being the only exendin derivative that, in a (terminated) phase 3 RCT, showed kidney benefit [HR 0.68 (95% CI 0.570.79)] and a reduction in the primary MACE outcome in T2DM patients with a history of CVD or CKD plus at least one other cardiovascular risk factor [57]
The OASIS 4 Phase 3 trial demonstrated a mean weight loss of approximately 13.6% to 16.6% with oral semaglutide 25 mg at 64 weeks depending on the analysis method used
As mentioned earlier, GLP-1 RAs function similarly to statins by inhibiting HMG-CoA reductase, suggesting that GLP-1 RAs can be prescribed as not only an antidiabetic medication but also as a cholesterol-lowering medication that can reduce the prevalence of CVD [64,65,70-73]
How should I eat and exercise if Im on a GLP-1 medication
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