10.1016/j.bios.2019.111760 112
Strong preclinical evidence for tissue repair
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The protein expression and activation of FAK and paxillin were determined by Western blot analysis, and the phosphorylation levels of both FAK and paxillin were dose-dependently increased by BPC-157, while the total amounts of protein were unaltered
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For example, if phenytoin levels are therapeutic, the administration of a drug competing for protein binding could double the free phenytoin level (if protein binding decreases from 90% to 80%)