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doi: 10.1016/0041-008x(85)90363-1

In addition, some authors investigated the risk associated with serum UA levels in a large cohort of patients with tauopathies (including subgroups with progressive supranuclear palsy, AD, and frontotemporal dementia) [222]

At study end, the dogs showed a decrease in overall storm-related anxiety, as well as reductions in stress-related behaviors

This shows the causal pathway whereby psychological trauma compromises gut barrier function and intestinal inflammation through stress hormone signaling

In the long run, this leads to improved health and improved healthspan

PPA is a metabolic by product of intestinal bacteria and possesses the capability to cross the gutblood and gutbrain barriers