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Studies have demonstrated that mice treated with Fasciola hepatica -excretory/secretory (Fh-ES) can imprint a lasting memory on HSCs in the BM through metabolic and transcriptional rewiring (249)

240,241,242 Early studies on ASD-associated DNA methylation focused on several candidate genes, such as MECP2 , glutamate decarboxylase 65 ( GAD65 ), reelin ( RELN ), oxytocin receptor ( OXTR ), SHANK3 and UBE3A

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Initial single-cell preprocessing, including dataset integration, graph-based clustering, and low-dimensional embedding, was carried out in R with Seurat (version 4) 33

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