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Reduction-oxidation state and protein degradation in skeletal muscle of fasted and refed rats

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Figure 1 gives an overview of the physiological actions of GLP-1 and GIP on various organ systems (47)

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For instance, the American Diabetes Association only recommends the use of GLP-1 drugs for weight loss for those with a body mass index, or BMI, of at least 30, or among those with a BMI of 27 or greater if they have at least one other condition such as type 2 diabetes, hypertension or high cholesterol

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Because of these variables, prescribing decisions are made exclusively by licensed healthcare professionals following review of an individual's medical history and risk profile

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