Why the reduced (GSH) form matters Glutathione is a tripeptide of cysteine, glutamic acid and glycine, present in every cell and often called the bodys master antioxidant for its central role in neutralising free radicals and regenerating other antioxidants like vitamins C and E
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D.KeshavanM
The reaction mechanism for roGFP2(S 2 ) as a model non-glutathione disulfide substrate resembles the first part of the GSH-dependent reduction of the sulfenic acid of human peroxiredoxin 6 that is catalyzed by glutathione transferase P1-1 (which shares several structural features with glutaredoxins) 7,80,81,82
[PubMed: 31802331] 26
Glutathione is a powerful antioxidant composed of three amino acids that protect cells from damage caused by free radicals, toxins, drugs, environmental pollutants, and oxidative stress