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DMSO also has an anti-inflammatory effect which can prevent astrocytic damage and activation due to inflammatory mediated damage by ROS ( Following TBI, oxidative stress in this study was evaluated by measuring the levels of SOD, CAT, GPx, and MDA as indicators of enzymatic antioxidant activity and lipid peroxidation respectively

Astrocyte functions in the copper homeostasis of the brain

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H 2 S-Induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response

Food and Drug Administration and U.S

designed a nanoplatform (AS_LIG@PPGC NPs) co-encapsulating astragaloside IV (AS) and ligustrazine (LIG), which demonstrated potent anti-fibrotic efficacy through dual-pathway suppression of NOX4-mediated ROS/p38 MAPK and NLRP3 signaling, reducing ROS generation while disrupting the self-amplifying loop between NOX4 activation and inflammasome formation (Zheng et al., 2024)