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Importantly, the SmPC notes that dose escalation can be delayed by an additional 4 weeks if adverse effects persist, allowing for better tolerability

Esther Menendez, University of Evora, Portugal Updates Copyright 2021 Hu, Chen, Luo, Zou, Xie, He, Li and Cheng

Despite the higher overall incidence of adverse events, discontinuation rates due to adverse events were similar between the semaglutide and placebo groups (2.6% vs

Zhang H et al., 2015)

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