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FDA posted a Warning Letter to CJ Labs (Miami, Florida) dated November 1, 2011 regarding serious violations of Good Manufacting Practices in the production of its Milk Thistle and L-Carnitine supplements

In rare cases, microdosing may be considered for patients who experience severe side effects or for super responders who lose excessive weight even on the lowest approved doses, but this approach is off-label and should be individualized under expert supervision

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Eng kept going anyway

This is partly related to reduced caloric intake