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In June 2022, both the FDA and the EMA authorized the medication for facilitating weight loss

The 2024 Cureus systematic review by Jaiswal and Jawade reaches the same conclusions across more than 60 cited studies: the wound-healing cascade and the delivery enhancement are two separable mechanisms, and which one dominates depends on needle depth, needle architecture, and how the serum is introduced [1]

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Brand name formulations like Zepbound and Mounjaro sidestep this entirely with pre-filled pens