Gradually increase fiber intake to avoid sudden digestive upset
Log any of the 18 most common GLP-1 side effects - nausea, constipation, heartburn, fatigue, food noise, and the rest - plus unlimited custom symptoms, each on a 0-10 severity scale with a timestamp
A thorough personal and family medical history should identify contraindications to either therapy, including history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (contraindications to GLP-1/GIP therapy), and history of breast cancer, endometrial cancer, unexplained vaginal bleeding, active liver disease, or thromboembolic disease (potential contraindications to HRT)
doi: 10.1210/en.2012-1983 137 Candelario-JalilEGonzlez-FalcnAGarca-CabreraMAlvarezDAl-DalainSMartnezGet al
Research in recent years has focused on GLP-1RAs stimulating the therapeutic target of GLP-1R [96]
This matters with GLP-1 treatment because dosing, nausea management, hydration, protein intake, and long-term planning all affect the experience