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[Epub ahead of print] Lewis KA et al

High dosages of equine chorionic gonadotropin exert adverse effects on the developmental competence of IVF-derived mouse embryos and cause oxidative stress-induced aneuploidy

GI side effects during escalation vs maintenance Both compounds share an important characteristic: most gastrointestinal side effects occur during dose escalation, not during maintenance

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These results suggest that mitochondrial iron overload and lipid ROS accumulation play an important role in oxidative stress-induced ferroptosis in cardiomyocytes

Jen Riegle of the Integrative Healers Action Network