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Copyright 2011 Saunders, An Imprint of Elsevier Available at: Accessed 6/29/2012 Rezaei Kelishadi M, Alavi Naeini A, Askari G, Khorvash F, Heidari Z

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Hypothyroidism contributes to OxS through an inefficient antioxidant defence system, opposite to hyperthyroidism, where increased ROS production promotes OxS and oxidative damage of thyroid cells ( Figure 1 ) (46)

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