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The best dose is the one that helps you lose weight safely with manageable side effects

High-dose supplementation, particularly hydroxocobalamin injections, has been associated with acne-like eruptions and rosacea flare-ups in susceptible individuals

These are more considerations of medications affecting vitamin status (rather than the vitamin affecting the medication), but they illustrate the clinical judgment required when co-administering this injection with certain treatments

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Its also smart to wear loose clothing and plan for light activity post-appointment

Interactions This list may not describe all possible interactions