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Comparison with Topiramate: The study matched 11,000 GLP-1 users against 11,000 topiramate users, adjusting for age, BMI, and prior health conditions

The side effects associated with these meds do generally improve after a bit and while nausea is very common, constipation is a close second and can be very bothersome for patients

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1 For example, liraglutide treatment led to substantial PASI score reduction alongside improvements in both body mass index (BMI) and hemoglobin A1C (HbA1c)

You should not expect to feel "different" overnight