2,5 In our cases, patients received relatively high doses with serum concentrations in the therapeutic range, and developed marked cutaneous hyperpigmentation
As for comfort, the first pass will tingle but numb the face for the rest of the application
Patients should contact their GP or healthcare provider promptly if they experience: Sudden or rapid swelling of the ankles, feet, or legs Facial swelling , particularly involving the lips, tongue, or throat (which may indicate angioedemaa medical emergency) [4] Swelling accompanied by shortness of breath , chest pain, or difficulty breathing Significant weight gain (more than 23 kg in a few days) without clear dietary explanation Swelling associated with abdominal distension or discomfort Reduced urine output or changes in urine colour Hot, red, painful swelling in one leg (which could indicate deep vein thrombosis) Seek immediate medical attention (call 999 or attend A&E) if swelling is accompanied by: Severe difficulty breathing or wheezing Chest pain or pressure Swelling of the face, lips, or tongue that affects breathing or swallowing Sudden severe abdominal pain (which could indicate pancreatitis, a rare but serious GLP-1 side effect) [1] [4] Sudden breathlessness or pleuritic chest pain (which could indicate pulmonary embolism) Contact NHS 111 for urgent advice if you're unsure about the severity of your symptoms but are concerned
and received consulting fees from Cogent Biosciences and Blueprint Medicines
Cada frasco contiene un suministro para 1 mes y se fabrica en una instalacin certificada cGMP en EE
Patient characteristics associated with treatment discontinuation were similar for GLP-1 receptor agonists and SGLT2 inhibitors
