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GLP-1 therapy works best when paired with professional follow-up, individualized dosing, and a supportive healthcare team

The most remarkable clinically Important pharmacokinetic characteristic is the difference between the short-acting and continuous-acting compounds (Table 1) [13]

This assessment focused on various factors including randomized sequence generation, treatment allocation concealment, blinding, completeness of outcome data, as well as selective outcome reporting and other potential sources of bias

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Mazdutide (IBI362 or LY3305677) is a once-weekly oxyntomodulin analogue which acts both on GLP-1 and glucagon receptors [65]

Lancet 394:131138 Tuttle KR, Lakshmanan MC, Rayner B, Busch RS, Zimmermann AG, Woodward DB et al (2018) Dulaglutide versus insulin glargine in patients with type 2 diabetes and moderate-to-severe chronic kidney disease (AWARD-7): a multicentre, open-label, randomised trial