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While results vary, clinical studies on the abdomen and flanks have shown average waistline reduction was about one dress or pant size (about one inch), with some patients losing up to two and one-half inches

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Hiccups (Singultus): A Perspective Analysis, Schematic, Overview, and Its Prevention and Treatment

(2018) 42 Suppl 1:S104S8

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Mechanism involves NO system modulation (homeostatic regulationupregulating when deficient, moderating when excessive), VEGF/VEGFR2 upregulation for angiogenesis, FAK-paxillin pathway activation for cell migration (40% increase per Chang et al.), and EGR-1 transcription factor upregulation for growth factor sensitivity