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At neutral pH, peptides with hydrophobic sequences or isoelectric points near or above physiological pH tend to self-associate through hydrophobic interactions and hydrogen bonding forming insoluble aggregates or gels that resist dissolution

1 Introduction Neurodegenerative diseases such as Alzheimers disease (AD), Parkinsons disease (PD), and multiple sclerosis (MS) are characterized by progressive nerve damage and chronic inflammation

P values were adjusted for multiple testing using BH FDR correction

Am J Phys Med Rehabilt 97(4):248254 Meheux CJ, McCulloch PC, Lintner DM, Varner KE, Harris JD (2016) Efficacy of intra-articular platelet-rich plasma injections in knee osteoarthritis: a systematic review

At the time, the FDAs panel of pharmacy advisors voted overwhelmingly that the peptides did not meet the criteria for substances that can be safely compounded

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