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These include its comparatively high utilization of oxygen and therefore generation of free radical byproducts, its modest antioxidant defenses, its lipid-rich constitution that provides substrates ready for oxidation, the reducing potential of certain neurotransmitters, and the presence of redox-catalytic metals, like iron and copper (47)

It has a very high turnover rate (6 10 6 molecules of H 2 O 2 to H 2 O and O 2 min 1 ) and is unique amongst antioxidant enzymes in not requiring a reducing equivalent

Nicotinic acid phosphoribosyltransferase regulates cancer cell metabolism, susceptibility to NAMPT inhibitors, and DNA repair

Mitchell DA Darobactin Substrate Engineering and Computation Show Radical Stability Governs Ether versus CC Bond Formation

Phytochemicals from Indian Ethnomedicines: Promising Prospects for the Management of Oxidative Stress and Cancer

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