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67 Although people with significant psychiatric illness are typically excluded from clinical trials, no increase in psychiatric disorders has been observed in these studies

The GLP-1 analogs liraglutide and semaglutide reduce atherosclerosis in ApoE / and LDLr / mice by a mechanism that includes inflammatory pathways

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In addition, the endoplasmic reticulum (ER) is one of the important places where redox reactions occur in cells, which can produce H 2 O 2 and ROS (Varlamova, 2018)

Diabetes Obes Metab (2017) 19(4):52436

These treatments include the use of antioxidants (e.g., resveratrol, curcumin, and quercetin), aldose reductase inhibitors, and protein aggregation inhibitors that have demonstrated potential utility in in vitro and in vivo studies