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Despite the concerns that oral CoQ 10 supplementation may excessively raise the tissue CoQ 10 concentrations in humans [43,54,55], the tissue CoQ 10 uptake in a healthy individual is relatively low due to its ongoing endogenous biosynthesis [56]

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3ce), although the microarray analysis revealed up-regulation and enrichment in gene sets related to NASH in MCD versus M + Fc-GLP-1 group (Supplementary Table 3)

2019 Sep;7(9):e21

BCL2 family inhibitors, such as ABT-263 and ABT-737 22,23,24 , that target BCL2 and BCL-XL, or S63845, an MCL-1 inhibitor 25 , are also senolytic

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