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The broader copper peptide network The paper also notes that copper peptide complexes (including the related GHK-Cu) are known to increase VEGF (vascular endothelial growth factor) production and decrease TGF-1 secretion by dermal fibroblasts

NLRP3 senses a wide array of endogenous and exogenous danger signals, including microbial products, environmental toxins, and host-derived DAMPs, making it a central player in inflammatory responses

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Exosomal RNAs, such as miR-4443, modulate FSP1 expression, a glutathione-independent ferroptosis suppressor, altering cellular resistance to lipid peroxidation and contributing to disease outcomes [102] (Fig

Studies have shown that HLA-DR2 haplotypes, particularly DRB5*01 + -DRB1*1501 + -DQB1*0602-, may play a role in the development of MS [152, 153]

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