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Leptin is considered to be a good predictor of growth hormone (GH) burst, cortisol, estradiol, and thyroid hormone levels and its receptor is widely distributed throughout the body suggesting a pivotal role in mediating the hormonal adaptation to chronic starvation
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Adequate hydration and regular small meals can help mitigate this effect
High-fat foods may trigger nausea or digestive discomfort when combined with semaglutide, while protein-rich meals enhance satiety and preserve muscle mass during weight loss
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