Thus, it is clinically recommended to give priority to drugs that have proven effects in all phases of bipolar disorder [35]
[PMID: 28660890]( Lindenbaum J, Healton EB, Savage DG, et al
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(2) Emulsion-evaporation method in which PLGA and agents to be encapsulated are dissolved in a volatile water-immiscible organic solvent, which is emulsified into aqueous external phase followed by evaporation of the organic solvent to form PLGA nanoparticles