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The pivotal Phase 2 trial (Jastreboff et al., 2023) did not stratify results by time of injection, and no head-to-head timing studies have been conducted to date

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Blood 2004

The types of controlled release systems available without significantly losing activity of the otic agent are determined using the teachings, examples, and principles disclosed herein An example of a conventional microencapsulation process for pharmaceutical preparations is shown in U.S