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Similar content being viewed by others Introduction Many metabolic disorders, including fatty liver disease, obesity, and type 2 diabetes mellitus (T2DM), are associated with insulin resistance (IR)

In the United States, supplements are regulated by the FDA as food products rather than drugs

Phentermine is FDA-approved only for short-term use (up to 12 weeks)

People will have to be on these drugs long-term or the weight will come back on, says Charlie Seltzer, MD , a board-certified obesity medicine doctor in Philadelphia

Such combination pharmacotherapy may achieve greater reduction of body weight in two ways