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Binding or wrapping the chest is no longer recommended because it restricts lung expansion and increases infection risk

Spray administration: Administer a measured amount of the TB-500 nasal spray by gently pressing the applicator, releasing the spray into the subject's nostril

Laimer M et al

In women , it triggers ovulation and luteal progesterone production

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Real-world data from clinics offering this combination protocol suggests enhanced fat loss compared to tirzepatide alone, but these observations come from uncontrolled clinical settings and cannot substitute for randomized controlled trials