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Months 2 to 4: Renewal of consistent weight loss as doses are titrated upward
During this phase, eat normally but pay attention to portion sizes
(August 2022)
Semaglutide, a glucagon-like peptide-1 agonist, is effective for weight loss, but the spectrum of side effects is still being discovered
Timelines vary by the individual, health status, and how well foundational habits support recovery
Glucagon receptor agonism increases hepatic glucose output and is hypothesised to promote lipolysis and increase energy expenditure, though the magnitude of this effect in humans is uncertain and context-dependent
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