(2010) showed that soy phytoestrogens modify DNA methylation of GSTP1, RASSF1A, EPH2, and BRCA1 TSG promoters in prostate cancer cells
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However, Chu found that activation of p53 alone did not significantly downregulate GSH/GSSG ratio, glutathione levels, and GPX4 activity in human cancer cells
Attele A.S., Wu J.A., Multiple constituents and multiple actions., Biochem
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This delivery method protects the glutathione from stomach acid and allows for maximum absorption through the intestinal lining