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Causality is difficult to prove, yet the pattern has made many dermatologists uneasy

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Growth hormone has approved clinical indications and robust human RCT data

quasi-static snapshots perturbation-based responses probabilistic state comparisons Comparisons: baseline vs post-stimulation control vs disease immature vs mature networks stable vs destabilized states What I Anticipate : functional patient stratification drug screening based on network response perturbation-guided personalized treatment Direction:Personalized psychiatry pharmacovigilance #neuropsychiatry To view or add a comment, sign in Trained in both neurology and psychiatry, David Perez MD, MMSc, FAAN, FANPA, FAPA has long been fascinated with functional neurological disorder, or FND, a mysterious condition that intersects both disciplines

The -toxin simultaneously activates the ERK1/2-nuclear factor-kB (NF-kB) and p38 mitogen-activated protein kinases (MAPK) cascades, which promote the expression and stabilization of interleukin-8, respectively (Oda et al., 2012)

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