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Tirzepatide is a dual GIP/GLP-1 agonist that targets two incretin receptors simultaneously, producing more pronounced metabolic effects

In addition, brain microglia-derived cytokines (IL-1, IL-6, IL-12, and TNF) become elevated and appear to facilitate disease progression [46]

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Pharm Pharmacol Commun 6(11):517520 [Google Scholar] Panda S, Kar A (2001) Inhibition of T3 production in levothyroxine-treated female mice by the root extract of Convolvulus pluricaulis