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Furthermore, iHLOs enable patient-specific modeling, providing a platform for precision medicine tailored to individual genetic and pathological conditions 12,13

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10.1152/physrev.00050.2017 9

In summary, there is a complex association between autophagy and ferroptosis

The high consumers of marine sources of omega 3 fatty acids with the reduced GST activity polymorphisms had at least a 64% reduction of risk compared to the low consumer counterparts, with some polymorphisms experiencing an even greater protection