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However, GLP-1RAs should be considered as the preferential add-on therapy in T2DM patients with CKD in case of persistent albuminuria and/or uncontrolled metabolic risks (i.e., inadequate glycemic control, hypertension, overweight/obesity)

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These changes reflect meaningful improvements in overall metabolic wellness rather than cosmetic or superficial benefits

H.MaitiP.et al (2019)