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While not statistically significant due to wide confidence intervals, the trend actually favored tirzepatide

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But managing complex therapies such as GLP-1s outside traditional benefit and monitoring systems can create gaps in follow-up and oversight. The Pulse Survey found that Americans recognize a need for some management of access to GLP-1s

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The SELECT trial, which studied semaglutide in cardiovascular outcomes across nearly 18,000 people with obesity and heart disease risk, similarly found no elevated musculoskeletal injury rates compared to control