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Samuel VT, Liu ZX, Wang A, Beddow SA, Geisler JG, Kahn M, Zhang XM, Monia BP, Bhanot S, Shulman GI (2007) Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease

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At the organ level, semaglutide promoted anti-fibrotic and metabolic remodelling by coordinating the downregulation of profibrotic signalling and extracellular matrix protein transcripts, while simultaneously shifting metabolic pathways towards fat oxidation and amino acid catabolism

Hill, B